Luteal Prostaglandin F2α: New Concepts of Prostaglandin F2α Secretion and Its Actions within the Bovine Corpus Luteum - Review -
نویسندگان
چکیده
منابع مشابه
Early transcriptome responses of the bovine midcycle corpus luteum to prostaglandin F2α includes cytokine signaling.
In ruminants, prostaglandin F2alpha (PGF2α)-mediated luteolysis is essential prior to estrous cycle resumption, and is a target for improving fertility. To deduce early PGF2α-provoked changes in the corpus luteum a short time-course (0.5-4 h) was performed on cows at midcycle. A microarray-determined transcriptome was established and examined by bioinformatic pathway analysis. Classic PGF2α eff...
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Luteinizing hormone (LH) regulates several ovarian functions. However, the luteoprotective mechanisms of LH involved in the maintenance of bovine corpus luteum (CL) function are not well understood. Since prostaglandin F2α (PGF), PGE2 and progesterone (P4) are well documented as antiapoptotic factors in the bovine CL, we hypothesized that LH protects the CL by stimulating the local production a...
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BACKGROUND The goal of this study was to examine the response of the cyclic corpus luteum of cows to the administration of a prostaglandin F2α analogue (PGF) during the transition of refractoriness to responsiveness by investigating ultrasonographic changes in the corpus luteum and changes in plasma progesterone concentration in cows following the administration of PGF 3 and 5 days after ovulat...
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The objective was to determine the effects of exogenous prostaglandin F(2α) (PGF), with or without progesterone treatment, on first ovulation in prepubertal heifers. We tested the hypothesis that PGF has a luteolysis-independent ovulatory effect in cattle. Crossbred Angus heifers (12 to 14 mo old, 250 kg body weight, and an average body condition score of 3 out of 5) were examined by transrecta...
متن کاملRapid Accumulation of Polymorphonuclear Neutrophils in the Corpus luteum during Prostaglandin F2α-Induced Luteolysis in the Cow
Prostaglandin F(2α) (PGF(2α)) induces luteolysis within a few days in cows, and immune cells increase in number in the regressing corpus luteum (CL), implying that luteolysis is an inflammatory-like immune response. We investigated the rapid change in polymorphonuclear neutrophil (PMN) numbers in response to PGF(2α) administration as the first cells recruited to inflammatory sites, together wit...
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ژورنال
عنوان ژورنال: Asian-Australasian Journal of Animal Sciences
سال: 2000
ISSN: 1011-2367,1976-5517
DOI: 10.5713/ajas.2000.390